amadeiglab

Publications

Here are some highlights of our publications followed by all our publications below.

Highlighted

Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development
Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development
Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, Ron Hadas, Gianluca Amadei, Yonatan Stelzer, Magdalena Zernicka-Goetz
Cell Stem Cell  ·  01 Oct 2022  ·  doi:10.1016/j.stem.2022.08.013
Embryo model completes gastrulation to neurulation and organogenesis
Embryo model completes gastrulation to neurulation and organogenesis
Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, …, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz
Nature  ·  25 Aug 2022  ·  doi:10.1038/s41586-022-05246-3
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro
Gianluca Amadei, Kasey Y.C. Lau, Joachim De Jonghe, Carlos W. Gantner, Berna Sozen, Christopher Chan, Meng Zhu, Christos Kyprianou, Florian Hollfelder, Magdalena Zernicka-Goetz
Developmental Cell  ·  01 Feb 2021  ·  doi:10.1016/j.devcel.2020.12.004

All

2023

Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitro
Assembly of complete mouse embryo models from embryonic and induced stem cell types in vitro
Kasey Y. C. Lau, Gianluca Amadei, Magdalena Zernicka-Goetz
Nature Protocols  ·  11 Oct 2023  ·  doi:10.1038/s41596-023-00891-y
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content
spinDrop: a droplet microfluidic platform to maximise single-cell sequencing information content
Joachim De Jonghe, Tomasz S. Kaminski, David B. Morse, Marcin Tabaka, Anna L. Ellermann, …, Charlotte E. Handford, Gregory M. Findlay, Magdalena Zernicka-Goetz, Sarah A. Teichmann, Florian Hollfelder
Nature Communications  ·  08 Aug 2023  ·  doi:10.1038/s41467-023-40322-w
Behind the developing brains and beating hearts of stem cell-derived embryo models
Behind the developing brains and beating hearts of stem cell-derived embryo models
Gianluca Amadei, David M. Glover
Open Biology  ·  01 Jan 2023  ·  doi:10.1098/rsob.220325
Generation of Stem Cell-Based Mouse Embryo-Like Structures
Generation of Stem Cell-Based Mouse Embryo-Like Structures
Charlotte E. Handford, Pallavi Panda, Ikbal B. Mohammad Choudhury, Gianluca Amadei, Magdalena Zernicka-Goetz
Embryo Models In Vitro  ·  01 Jan 2023  ·  doi:10.1007/7651_2023_493

2022

Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development
Mouse embryo model derived exclusively from embryonic stem cells undergoes neurulation and heart development
Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, Ron Hadas, Gianluca Amadei, Yonatan Stelzer, Magdalena Zernicka-Goetz
Cell Stem Cell  ·  01 Oct 2022  ·  doi:10.1016/j.stem.2022.08.013
Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart-like structure.
Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart-like structure.
Gianluca Amadei, Charlotte E. Handford, David Glover, Magdalena Zernicka-Goetz
Research Square Platform LLC  ·  26 Aug 2022  ·  doi:10.21203/rs.3.pex-2006/v1
Embryo model completes gastrulation to neurulation and organogenesis
Embryo model completes gastrulation to neurulation and organogenesis
Gianluca Amadei, Charlotte E. Handford, Chengxiang Qiu, Joachim De Jonghe, Hannah Greenfeld, …, Michael B. Elowitz, Florian Hollfelder, Jay Shendure, David M. Glover, Magdalena Zernicka-Goetz
Nature  ·  25 Aug 2022  ·  doi:10.1038/s41586-022-05246-3
Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart
Stem cell-derived mouse embryos develop within an extra-embryonic yolk sac to form anterior brain regions and a beating heart
Gianluca Amadei, Charlotte E Handford, Joachim De Jonghe, Florian Hollfelder, David Glover, Magdalena Zernicka-Goetz
Cold Spring Harbor Laboratory  ·  02 Aug 2022  ·  doi:10.1101/2022.08.01.502375
Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development
Mouse-embryo model derived exclusively from embryonic stem cells undergo neurulation and heart development
Kasey Y.C. Lau, Hernan Rubinstein, Carlos W. Gantner, Gianluca Amadei, Yonatan Stelzer, Magdalena Zernicka-Goetz
Cold Spring Harbor Laboratory  ·  02 Aug 2022  ·  doi:10.1101/2022.08.01.502371

2021

Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro
Inducible Stem-Cell-Derived Embryos Capture Mouse Morphogenetic Events In Vitro
Gianluca Amadei, Kasey Y.C. Lau, Joachim De Jonghe, Carlos W. Gantner, Berna Sozen, Christopher Chan, Meng Zhu, Christos Kyprianou, Florian Hollfelder, Magdalena Zernicka-Goetz
Developmental Cell  ·  01 Feb 2021  ·  doi:10.1016/j.devcel.2020.12.004

2020

Basement membrane remodelling regulates mouse embryogenesis
Basement membrane remodelling regulates mouse embryogenesis
Christos Kyprianou, Neophytos Christodoulou, Russell S. Hamilton, Wallis Nahaboo, Diana Suarez Boomgaard, Gianluca Amadei, Isabelle Migeotte, Magdalena Zernicka-Goetz
Nature  ·  06 May 2020  ·  doi:10.1038/s41586-020-2264-2

2018

Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures
Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures
Berna Sozen, Gianluca Amadei, Andy Cox, Ran Wang, Ellen Na, …, Thierry Voet, Geert Michel, Naihe Jing, David M. Glover, Magdalena Zernicka-Goetz
Nature Cell Biology  ·  23 Jul 2018  ·  doi:10.1038/s41556-018-0147-7

2015

A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis
A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis
Gianluca Amadei, Mark A. Zander, Guang Yang, Jason G. Dumelie, John P. Vessey, Howard D. Lipshitz, Craig A. Smibert, David R. Kaplan, Freda D. Miller
The Journal of Neuroscience  ·  25 Nov 2015  ·  doi:10.1523/jneurosci.2172-15.2015

2012

An Asymmetrically Localized Staufen2-Dependent RNA Complex Regulates Maintenance of Mammalian Neural Stem Cells
An Asymmetrically Localized Staufen2-Dependent RNA Complex Regulates Maintenance of Mammalian Neural Stem Cells
John P. Vessey, Gianluca Amadei, Sarah E. Burns, Michael A. Kiebler, David R. Kaplan, Freda D. Miller
Cell Stem Cell  ·  01 Oct 2012  ·  doi:10.1016/j.stem.2012.06.010

2011

Quantification of character‐impacting compounds in <i>Ocimum basilicum</i> and 'Pesto alla Genovese' with selected ion flow tube mass spectrometry
Quantification of character‐impacting compounds in Ocimum basilicum and 'Pesto alla Genovese' with selected ion flow tube mass spectrometry
Gianluca Amadei, Brian M. Ross
Rapid Communications in Mass Spectrometry  ·  22 Dec 2011  ·  doi:10.1002/rcm.5293

2010

The reactions of a series of terpenoids with H<sub>3</sub>O<sup>+</sup>, NO<sup>+</sup> and O studied using selected ion flow tube mass spectrometry
The reactions of a series of terpenoids with H3O+, NO+ and O studied using selected ion flow tube mass spectrometry
Gianluca Amadei, Brian M. Ross
Rapid Communications in Mass Spectrometry  ·  14 Dec 2010  ·  doi:10.1002/rcm.4845